The methods on this package are described in the vignette or in the article 'Multivariate Method for Inferential Identification of Differentially Expressed Genes in Gene Expression Experiments' by J. It uses artificial components, close to the data's principal components but with an exact interpretation in terms of differential genetic expression, to identify differentially expressed genes while controlling the false discovery rate (FDR). Additional functions provided in this package like 'get_expression' and 'plot_expression' facilitate exploring the expression data.Īcde - This package provides a multivariate inferential analysis method for detecting differentially expressed genes in gene expression data. 'aba_enrich' interfaces the ontology enrichment software FUNC to perform the statistical analyses. The core function 'aba_enrich' integrates the expression of the candidate gene set (averaged across donors) and the structural information of the brain using an ontology, both provided by the Allen Brain Atlas project. There are 80 new packages in this release of Bioconductor.ĪBAEnrichment - The package ABAEnrichment is designed to test for enrichment of user defined candidate genes in the set of expressed genes in different human brain regions.
Bioconductor 3.2 has been designed expressly
To update to or install Bioconductor 3.2:ġ. * Packages removed from Bioconductor since the last release You should plan to migrate to Mavericks or newer before the next release (in the Spring of 2016). Note also that this is the last version of Bioconductor to be supported on Snow Leopard. However, this new release should still be basically usable on Snow Leopard. Note: The Snow Leopard builds are a few days behind, because of some issues that we are working through. Release includes an updated Bioconductor
To existing packages Bioconductor 3.2 is compatible with R 3.2,Īnd is supported on Linux, 32- and 64-bit Windows, and Mac OS X. There are 80 new software packages, and many updates and improvements Software packages, 257 experiment data packages, and 917 We are pleased to announce Bioconductor 3.2, consisting of 1104